关节牵伸术治疗膝骨关节炎的作用机制Mechanism of joint distraction in the treatment of knee osteoarthritis
邵一鸣;张濛;张可方;张新安;连鸿凯;
摘要(Abstract):
关节牵伸术已经成为考虑进行人工膝关节置换术的终末期膝骨关节炎患者的一种保留关节的治疗方法。目前,有几种机制被认为与关节牵伸术所观察到的临床疗效和结构改变有关。为全面了解关节牵伸术治疗膝骨关节炎的修复作用,本文从生物力学变化、关节周围骨质改变、关节源性间充质干细胞的黏附及关节内分子环境的变化等方面对关节牵伸术的治疗机制进行综述。
关键词(KeyWords): 关节牵伸术;骨关节炎;膝关节;生物力学;骨转换;间充质干细胞
基金项目(Foundation): 2021年度河南省高等学校重点项目(21A320038);; 河南省医学科技攻关计划联合共建项目(LHGJ20210035);河南省医学科技攻关计划联合共建项目(LHGJ20191059)
作者(Authors): 邵一鸣;张濛;张可方;张新安;连鸿凯;
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